SYNTHESIS, CHARACTERISATION AND ANTI BACTERIAL STUDIES OF (E)-2-(3,4,5- TRIMETHOXY BENZYLIDENE ) HYDRAZINE CARBOTHIOAMIDE

Abstract

The chemistry of macromolecule like shiff bases get major attension becouse of its immobilization activities and hence they are alternatives for biopolymer biosensors in lot of various industries. The polymer based macromolecule coordinate with metal and the resulting material act as sensors .In this work, we synthesised  (E)-2-(3,4,5trimethoxy benzylidene)hydrazinecarbothioamide and establish its structure through the analytical (elemental and TLC) and spectral (IR, H1 NMR and C13 NMR) methods of characterization .The structure of the ligand THC and its complexes were carried out. The changes in the structural features of the ligands are observed in the fingerprint region (4000-400 cm-1). The bands due to the metal ligand bonds are mainly observed in the far IR region (600-100 cm-1). In the present study, IR spectra of the compounds were recorded using Perkin Elmer spectrum RXI using KBr pellets at frequency range 4000-400 cm-1. 1H NMR of the ligands were recorded using Bruker 300 MHz Avance –II FT-NMR Spectrometer with DMSO-d6 as the solvent and TMS as internal standard. 13 C NMR of the synthesized compounds were recorded on 75 MHz Bruker Spectrometer at 298.6 K using DMSO-d6 as solvent.