Green Synthesis of Silver Nanoparticles Using Ginger Extract and Its Antioxidant (In Vitro) And Anticancer( Insilico) Study

Abstract

Herbal drug delivery is limited by poor solubility and bioavailability which can be overcome with suitable nanomaterials that will enhance their pharmacokinetics and performance. Optimization of this green synthesis would support the production of AgNPs with great therapeutic potentials. The present work is focused on discovering a new technique for green synthesis of metal nanoparticles of ginger water and methanolic extracts. The investigated samples were used to evaluate the antioxidant capacity and antimicrobial activity. The present study reveals that to separate and detect gingerol from ginger rhizome, to synthesis, characterize silver nanoparticles (AgNPs) using gingerol, to find out antibacterial activity against P.gingivalis, to screen the antioxidant activities of the AgNPs, to evaluate the anti-inflammatory and anticoagulant activity of AgNp and to find out the binding efficiency of Gingerol against breast cancer target.