COMPARATIVE STUDY OF SODIUM BOROHYDRIDE CATALYSED REDUCTION REATIONS: SYNTHESIS AND CHARACTERIZATION OF BENZYL ALCOHOL AND ANTIBACTERIAL ACTIVITY

Abstract

 The project of this thesis is the comparative study of sodium borohydride catalyzed reactions and to synthesize benzyl alcohol via the reduction reaction of Benzaldehyde. Then it will be check for antibacterial property using Disc Diffusion Method. The scope of the work is highly effective in medical field because of its Antibacterial property. In my work I have compared the sodium borohydride catalyzed reaction by taking ethyl acetoacetate for one reaction and Benzaldehyde for another reaction with sodium borohydride. Spectral (FT-IR) Method was used to establish the bond shifting of carbonyl group into hydroxyl group. The main objectives of the thesis Comparison sodium borohydride catalyzed reaction, Synthesis of benzyl alcohol, Detection of the compound by TLC, Characterization by FT-IR, Evaluation of anti-bacterial property.