The Internet of Things (IoT), hailed because the enabler of subsequent technological revolution, would require ubiquitous connectivity, context-aware and dynamic service mobility, and extreme security through the wireless network infrastructure. Artificial Intelligence (AI), thus, will play a serious role within the underlying network infrastructure. However, variety of challenges will Surface when using AI's concepts, tools and methods wireless networks employed by IoT . During this article, the most challenges in using AI within the wireless network infrastructure that facilitate end-to-end IoT communication are highlighted with potential generalized solution and future research directions.